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IP Chemo for Ovarian Cancer is Underused - National Cancer Institute

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Related Articles. Radiosensitizing Effect of Novel Phenylpyrimidine Compound. Methionine Gamma-Lyase from B. In some cases, chemotherapy may also be injected through a catheter thin tube directly into the abdominal cavity.

Should intraperitoneal chemotherapy become the standard of care for ovarian cancer?

This is called intraperitoneal IP chemotherapy. Chemo for ovarian cancer usually involves getting two different types of drugs together.


Getting a combination of drugs instead of just one drug alone seems to work better as a first treatment for ovarian cancer. These drugs are usually given as an IV put into a vein every 3 to 4 weeks.

The typical course of chemo for epithelial ovarian cancer involves 3 to 6 cycles of treatment, depending on the stage and type of ovarian cancer. A cycle is a schedule of regular doses of a drug, followed by a rest period.

Intraperitoneal Chemotherapy Fails to Improve Outcomes in Advanced Ovarian Carcinoma

Different drugs have varying cycles; your doctor will let you know what schedule is planned for your chemo. Epithelial ovarian cancer often shrinks or even seems to go away with chemo, but the cancer cells may eventually begin to grow again.

If the first chemo seemed to work well and the cancer stayed away for at least 6 to 12 months, it can be treated with the same chemotherapy used the first time. In some cases, different drugs may be used.

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For women who have stage III ovarian cancer cancer that has not spread outside the abdomen and whose cancers were optimally debulked no tumors larger than 1 cm after surgery , intraperitoneal IP chemotherapy might be given in addition to systemic chemo paclitaxel given in a vein. In IP chemotherapy, the drugs cisplatin and paclitaxel are injected into the abdominal cavity through a catheter thin tube. Clouser Lisa M. Front Matter Pages i-viii.

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Pages Current Chemotherapy of Ovarian Cancer. Principles of Intraperitoneal Chemotherapy. Back Matter Pages About this book Introduction Intraperitoneal chemotherapy is increasingly being used as first-line treatment for ovarian cancer.

Christine's HIPEC story of hope